Immuno-Chek G™ Camelid IgG is a point of care test to measure Camel, Llama and Alpacca Calf IgG in 10 min.
IgG levels of all calves or crias should be routinely measured after first suckling (between 24-48 hours old). Calves and crias are born with no circulating antibodies (IgG) and must receive adequate antibodies from the mother's colostrum. Up to 40% of newborn calves and crias have low IgG levels, placing them at high risk for infection, serious illness, or death. Low IgG may result from premature lactation, poor suckling, malabsorption, or low-quality colostrum. An IgG test measures whether a calf's IgG level is normal, low, or very low.
Checkout this video on running an IgG test with our cube reader.
Color intensity on Test Line is proportional to Camelid Calf or Cria IgG concentration.
Compare the relative intensities of the cassette lines to the Interpretation chart in the instructions.
This study, published in the American Journal of Veterinary Research in July 2000 Focuses on the passive transfer of colostral immunoglobulin G (IgG) in neonatal llamas and alpacas. It reveals that llamas and alpacas are born severely hypogammaglobulinemic, emphasizing the critical role of colostral intake in achieving adequate serum IgG concentrations. The research indicates that peak serum IgG concentrations develop between days 1 and 2 after birth, with no significant difference observed between llamas and alpacas. The optimal sampling time for assessing passive transfer status is recommended to be between 1 and 2 days postpartum. The study also addresses mortality rates associated with failure of passive transfer and suggests a threshold IgG concentration of 1,000 mg/dl at 48 hours of age as indicative of adequate passive transfer. Overall, the findings provide valuable insights into passive transfer management in these species.
This 2013 article by the Journal of Veterinary Diagnostic Investigation Using Cornell's samples emphasizes the importance of accurate measurement of immunoglobulin levels, particularly in diagnosing failure of passive transfer (FPT) in crias. The study aimed to assess the comparability of three commercially available immunologic assays for measuring serum immunoglobulin G (IgG) in alpacas and their precision. Samples from 91 alpacas were analyzed using radial immunodiffusion (RID) and two immunoturbidimetric (IT) assays. Results showed significant differences in IgG concentrations between the assays, with the RID and one IT assay yielding higher values than the other IT assay. Discordant results were observed in 1–17% of samples at an IgG threshold of 10 g/l. Electrophoresis revealed differences in assay standards, impacting results. The study suggests caution in interpreting camelid IgG data and highlights the need for standardized assays in diagnosing failure of passive transfer (FPT) in crias.
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